Exchange the real essences with a rune crafter there for your natures
The Nature Altar: Running for nature rune-crafters may be slightly different than running aion gold for law crafters.
The difference is that instead of returning to a bank (like in Draynor Village); you’ll be heading back to a General Store.
First off, find the world where the most nature runnings are taking place. Bring a decent amount of noted rune essences, as well as a decent amount of cash to buy back the essences, with you to the island of Karamja, that’s all you’ll need.
Start out by making your way towards the General Store south of the town of Brim haven past the narrow strip of land (you can make you way to the Brim haven dock by sailing from East Ardougne).
At the store, sell an appropriate amount of the noted essences to the shopkeeper and buy it back from him in order to get the real essences. Now, head southeast until you find yourself at the Nature altar near the mining camp.
Exchange the real essences with a rune crafter there for your natures (or whatever he/she is offering). Head back to the General Store and do exactly the same procedure until you are satisfied with your salary.